GNAS Monoclonal Antibody-MB67125

GNAS Monoclonal Antibody

Catalogue Numbers: MB67125-50, MB67125-100

Sizes: 50µl, 100µl

Product: Mouse IgM. Supplied in crude ascites with 0.01% sodium azide.

Swiss-Prot: Q6R0H7; P63094; Q9Z0F1

Host: Mouse

Reactivity: Mouse

Applications: WB

All Applications: WB (1/500 - 1/1000)

Background: Guanine nucleotide-binding proteins (G proteins) function as transducers in numerous signaling pathways controlled by G protein-coupled receptors (GPCRs). Signaling involves the activation of adenylyl cyclases, resulting in increased levels of the signaling molecule cAMP. GNAS functions downstream of several GPCRs, including beta-adrenergic receptors. XLas isoforms interact with the same set of receptors as Gnas isoforms.

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: Recognizes endogenous levels of GNAS protein.

Extra Notes: Western blot analysis of GNAS expression in mouse brain (A) whole cell lysates.

Bioworld Molecular Weight: ~ 50 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Name: GNAS complex locus

Immunogen: KLH-conjugated synthetic peptide of human GNAS. The exact sequence is proprietary.

Conjugate: Unconjugated

Modification: Unmodified