GNAS3 Polyclonal Antibody Sizes: 50μL, 100μL Catalogue Numbers: RA32482-50, RA32482-100 Lead times: 1-2 weeks, if manufacturer has product in stock Manufacturer/Ship Location: China Background: GNAS complex locus (GNAS) Homo sapiens This locus has a highly complex imprinted expression pattern. It gives rise to maternally, paternally, and biallelically expressed transcripts that are derived from four alternative promoters and 5' exons. Some transcripts contain a differentially methylated region (DMR) at their 5' exons, and this DMR is commonly found in imprinted genes and correlates with transcript expression. An antisense transcript is produced from an overlapping locus on the opposite strand. One of the transcripts produced from this locus, and the antisense transcript, are paternally expressed noncoding RNAs, and may regulate imprinting in this region. In addition, one of the transcripts contains a second overlapping ORF, which encodes a structurally unrelated protein - Alex. Alternative splicing of downstream exons is also observed, which results in different forms of the stimulatory G-protein alpha subunit, a key Reactivity: Human, Rat, Mouse Host: Rabbit Applications: WB, ELISA Clonality: Polyclonal Dilution: WB 1:500-2000 ELISA 1:5000-20000 Molecular Weight: 26 Protein Molecular Weight (kDa): 26 Storage: -20°C/1 year Human Gene ID: 2778 Human SwissProt Number: O95467 Condition: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. Research Use Only