Product Description

GNAZ (A12) Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS2996-50, BS2996-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Guanine nucleotide-binding proteins (G proteins) are involved as modμlators or transducers in various transmembrane signaling systems. G proteins are composed of 3 units, alpha, beta and gamma. The alpha chain contains the guanine nucleotide binding site. G protein z alpha, encoded by the GNAZ gene, is enriched in neural tissue and differs in sequence from other G alpha subunits. Alpha Subunits are encoded in 15 genes and several transcripts are alternatively spliced. Receptors may discriminate between splice variants, whether splice variants are functionally different in regμlating effectors is not known. All alpha subunits appear to be palmitoylated near the N-terminus.

Category: Primary Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: IHC

Alternate Names: Guanine nucleotide-binding protein G(z) subunit alpha, G(x) alpha chain, Gz-alpha, GNAZ, Gzα, Gz-α

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: Synthetic peptide, corresponding to the N-terminus of Human GNAZ.

Dilution: IHC:1:50~1:200

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: GNAZ (A12) polyclonal antibody detects endogenous levels of GNAZ protein.

Molecular Weight: ~ 41 kDa

Pathway: Phospholipase Signaling, SAPK JNK Signaling Cascades, G Protein-coupled Receptors Signaling to MAPK Erk,

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: P19086

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only