Product Description

GNG5 Polyclonal Antibody

Catalogue Numbers: BS61200-50, BS61200-100

Sizes: 50µl, 100µl

Alternative Name: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5; GNG5; GNGT5

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: P63218

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB

All Applications: WB: 1:500~1:1000

Background: Heterotrimeric G proteinsfunction to relay information from cell surface receptors to intracellular effectors. Each of a very broad range of receptors specifically detects an extracellular stimulus(a photon, pheromone, odorant, hormone or neuro transmitter) while the effectors(e.g., adenylcyclase),which act to generate one ormore intracellula rmessengers, are less numerous. In mammals, G protein α, β and γ polypeptides are encoded by at least 16, 4 and 7 genes, respectively. Most interest in G proteins has been focused on their α subunits,since these proteins bind and hydrolyze GTP andmost obvously regulate the activity of the beststudied effectors. Evidence, however, has established an important regulatory role for the βγ subunits. It is becoming increasingly clear that different G protein complexes expressed in diffeent tissues carry structurally distinct members of the γ aswell astheαand β subunits and that preferential associations between members of subunit families increase G protein functional diversity.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: GNG5 polyclonal antibody detects endogenous levels of GNG5 protein.

Bioworld Molecular Weight: ~ 7 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot (WB) analysis of GNG5 polyclonal antibody at 1:500 dilution Lane 1: HEK293T whole cell lysate
Lane 2: RAW264.7 whole cell lysate Lane 3: H9C2 whole cell lysate

Immunogen: A synthetic peptide corresponding to residues in Human GNG5.

Conjugate: Unconjugated

Modification: Unmodified