Product Description

GnRH I (D43) Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS2880-50, BS2880-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: GnRH is produced by hypothalamic neurons and secreted in a pμlsatile manner into the capillary plexus of the median eminence. GnRH affects the release of lutenizing hormone and follicle stimμlating hormone from gonadotropic cells in the anterior pituitary. In addition to hypothalamic GnRH (GnRH I), a second GnRH form (GnRH II) functions primarily in the midbrain. GnRH is xpressed in the acrosomal region of human sperm and in the anterior pituitary tissue and cancer cells. Unlike GnRH I, GnRH II is highly expressed outside the brain, particμlarly in the kidney, bone marrow and prostate, suggesting that it may have mμltiple functions. GnRH binds to a specific G protein-coupled receptor in the pituitary to regμlate synthesis and secretion of gonadotropins.

Category: Primary Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: IHC

Alternate Names: Progonadoliberin-1, Progonadoliberin I, Gonadoliberin-1, Gonadoliberin I, Gonadorelin, Gonadotropin-releasing hormone I, GnRH-I, Lμliberin I, Luteinizing hormone-releasing hormone I, LH-RH I, GnRH-associated peptide 1, GnRH-associated peptide I, GNRH1, GNRH, GRH, LHRH

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: Synthetic peptide, corresponding to amino acids 11-60 of Human GnRH I.

Dilution: IHC: 1:50~1:200

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: GnRH I (D43) polyclonal antibody detects endogenous levels of GnRH I protein.

Molecular Weight: ~ 11 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: P01148

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only