GNRHR Polyclonal Antibody
Sizes: 60μL, 120μL, 200μL
Catalogue Numbers: E-AB-12492-60, E-AB-12492-120, E-AB-12492-200
Citations, Manuals and MSDS Available upon request.
Abbreviation: GNRHR
Target Synonym: GnRH receptor; GnRH-R; GNRHR; GNRHR; GNRHR1; Gonadotropin releasing hormone receptor; gonadotropin-releasing hormone (type 1) receptor 1; Gonadotropin-releasing hormone receptor; GRHR; HH7; leutinizing-releasing hormone receptor; lh-rh; LHRHR; LRHR; luliberin receptor; luteinizing hormone releasing hormone receptor; type I GnRH receptor
Research Areas: Cancer, Neuroscience
Conjugation: Unconjugated
Host: Rabbit
Species Reactivity: Human, Mouse
Application: WB, ELISA
Isotype: IgG
Clonality: Polyclonal
UNIProt ID: P30968
Background: This gene encodes the receptor for type 1 gonadotropin-releasing hormone. This receptor is a member of the seven-transmembrane, G-protein coupled receptor (GPCR) family. It is expressed on the surface of pituitary gonadotrope cells as well as lymphocytes, breast, ovary, and prostate. Following binding of gonadotropin-releasing hormone, the receptor associates with G-proteins that activate a phosphatidylinositol-calcium second messenger system. Activation of the receptor ultimately causes the release of gonadotropic luteinizing hormone (LH) and follicle stimulating hormone (FSH). Defects in this gene are a cause of hypogonadotropic hypogonadism (HH). Alternative splicing results in multiple transcript variants encoding different isoforms. More than 18 transcription initiation sites in the 5' region and multiple polyA signals in the 3' region have been identified for this gene.
Concentration: 0.3 mg/mL
Immunogen: Synthetic peptide of human GNRHR
Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification Method: Affinity purification
Dilution: WB 1:500-1:2000
Calculated MW: 28kDa
Storage: -20°C/One year. Avoid freeze / thaw cycles.
Shipping: Ice bag
Research Use Only