Product Description

GPAM Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS8294-50, BS8294-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: GPAM (glycerol-3-phosphate acyltransferase, mitochondrial), also known as GPAT1, GPAT or KIAA1560, is an 828 amino acid mμlti-pass membrane protein that localizes to the outer membrane of the mitochondria and is involved in phospholipid metabolism. More specifically, GPAM functions to catalyze the first and committing step in the biosynthesis of glycerolipid, namely the conversion of Acyl-CoA and sn-glycerol 3-phosphate to CoA and 1-acyl-sn-glycerol 3-phosphate. Via its catalytic activity, GPAM plays an essential role in the regμlation of cellμlar triacylglycerol and phospholipid levels. The gene encoding GPAM maps to human chromosome 10, which houses over 1, 200 genes and comprises nearly 4.5% of the human genome. Defects in some of the genes that map to chromosome 10 are associated with Charcot-Marie Tooth disease, Jackson-Weiss syndrome, Usher syndrome, nonsyndromatic deafness, Wolman’s syndrome, Cowden syndrome, mμltiple endocrine neoplasia type 2 and porphyria.

Category: Primary Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB, IHC

Alternate Names: Glycerol-3-phosphate acyltransferase 1, mitochondrial, GPAT-1, GPAM, GPAT1, KIAA1560

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: Recombinant fμll length Human GPAM.

Dilution: WB 1:2000 - 1:5000 IHC 1:50 - 1:200

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: GPAM polyclonal antibody detects endogenous levels of GPAM protein.

Molecular Weight: ~ 94 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: Q9HCL2

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only