Product Description

GPBAR1 Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-93270-60, E-AB-93270-120, E-AB-93270-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: GPBAR1

Target Synonym: BG37; TGR5; M-BAR; GPCR19; GPR131

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human, Rat

Application: WB, IF

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: Q8TDU6

Background: This gene encodes a member of the G protein-coupled receptor (GPCR) superfamily. This enzyme functions as a cell surface receptor for bile acids. Treatment of cells expressing this GPCR with bile acids induces the production of intracellular cAMP, activation of a MAP kinase signaling pathway, and internalization of the receptor. The receptor is implicated in the suppression of macrophage functions and regulation of energy homeostasis by bile acids. Alternative splicing results in multiple transcript variants encoding the same protein.

Concentration: 1mg/mL

Immunogen: A synthetic peptide of human GPBAR1

Buffer: PBS with 0.05% proclin300, 50% glycerol, pH7.3.

Purification Method: Affinity purification

Dilution: WB 1:500-1:2000, IF 1:50-1:200

Calculated MW: 35kDa

Observed MW: 35KDa

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only