Product Description

GPBP1 Polyclonal Antibody

Product: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Sizes: 50µl, 100µl

Catalogue Numbers: BS65762-50, BS65762-100

Swiss-Prot: Q86WP2

Host: Rabbit

GPBP1 Polyclonal Antibody-BS65762

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Reactivity: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Sheep,

Applications: WB,

All Applications: WB=1:500-2000

Background: Vascular wall-linked protein, or Vasculin, is primarily expressed in the arterial wall and in plasma. It is also differentially expressed in human atherogenesis. Alternative splicing of exon 3 of the Vasculin gene produces three variants. Vasculin binds to and activates the minimal self-sufficient promoter element (MSPE) of the mouse Ada gene promoter and binds to and partially suppresses the GC-rich promoter of the nonhomologous human TOP2A gene promoter. It acts as a nuclear factor that can form complexes with TATA-binding proteins, transcription factors TFIIB and TFIIF, RNA polymerase II and p300. The regulated expression of Vasculin in plaques suggests that it may be involved in atherogenesis, and its presence in plasma may implicate Vasculin as a marker for atherosclerosis.

Purification and Purity: affinity purified by Protein A

Specificity: GPBP1 Polyclonal Antibody detects endogenous levels of GPBP1 protein.

Bioworld Molecular Weight: 53 kD

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Primary: Anti-GPBP1 at 1/1000 dilution, Primary: Anti-GPBP1 at 1/1000 dilution

Alternative Name: Vasculin; DKFZp761C169; GC rich promoter binding protein 1; GC-rich promoter-binding protein 1; GPBP; Gpbp1; GPBP1_HUMAN; MGC126339; SSH6; Vascular wall linked; Vascular wall-linked protein.聽聽

Immunogen: KLH conjugated synthetic peptide derived from human GPBP1/Vasculin:11-110/473

Modification: Unmodified

Conjugate: Unconjugated