Product Description

GPBP1 Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS65762-50, BS65762-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Vascμlar wall-linked protein, or Vascμlin, is primarily expressed in the arterial wall and in plasma. It is also differentially expressed in human atherogenesis. Alternative splicing of exon 3 of the Vascμlin gene produces three variants. Vascμlin binds to and activates the minimal self-sufficient promoter element (MSPE) of the mouse Ada gene promoter and binds to and partially suppresses the GC-rich promoter of the nonhomologous human TOP2A gene promoter. It acts as a nuclear factor that can form complexes with TATA-binding proteins, transcription factors TFIIB and TFIIF, RNA polymerase II and p300. The regμlated expression of Vascμlin in plaques suggests that it may be involved in atherogenesis, and its presence in plasma may implicate Vascμlin as a marker for atherosclerosis.

Category: Primary Antibody

Reactivity: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Sheep

Host: Rabbit

Applications: WB

Alternate Names: Vascμlin, DKFZp761C169, GC rich promoter binding protein 1, GC-rich promoter-binding protein 1, GPBP, Gpbp1, GPBP1_HUMAN, MGC126339, SSH6, Vascμlar wall linked, Vascμlar wall-linked protein.聽聽

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: KLH conjugated synthetic peptide derived from human GPBP1/Vascμlin:11-110/473

Dilution: WB=1:500-2000

Purification: affinity purified by Protein A

Specificity: GPBP1 Polyclonal Antibody detects endogenous levels of GPBP1 protein.

Molecular Weight: 53 kD

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: Q86WP2

Product: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Research Use Only