GPCR RDC1 Polyclonal Antibody-BS90593

GPCR RDC1 Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BS90593-50, BS90593-100

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: P25106(Human) P56485(Mouse) O89039(Rat)

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB, FC

All Applications: WB:1:1,000-1:5,000
FC:1:10-1:100

Background: Members of the C-X-C or α chemokine family are characterized by a pair of cysteine residues separated by a single amino acid and primarily function as chemoattractants for neutrophils. The C-X-C family includes IL-8, NAP-2, MSGA and stromal cell derived factor-1 (SDF-1). Receptors for the C-X-C family are G protein-coupled, seven pass transmembrane domain proteins and include proteins such as IL-8RA, IL-8RB, CXCR-3 and fusin (also designated LESTR or CXCR-4). C-X-C chemokine receptor type 7 (CXCR-7), also known as RDC-1, is a 362 amino acid receptor for SDF-1. Initially identified as a receptor for vasoactive intestinal peptide (VIP), it is now considered to be an orphan receptor. CXCR-7, with CSCR-4, also acts as a coreceptor for human immunodeficiency viruses (HIV). Highly expressed in monocytes, B-cells and basophils, and highly active in various biological processes, including cell growth, cell adhesion and tumor growth, CXCR-7 may play a role in tumorigenesis.

Purification and Purity: ProA affinity purified

Storage and Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Specificity: GPCR RDC1 polyclonal antibody detects endogenous levels of GPCR RDC1 protein.

Bioworld Molecular Weight: 41 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of GPCR RDC1 on PC-3M cells lysates using anti-GPCR RDC1 antibody at 1/1,000 dilution., Flow cytometric analysis of Jurkat cells with GPCR RDC1 antibody at 1/50 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated goat anti rabbit IgG was used as the secondary antibody

Alternative Name: CXC-R7, CXCR-7, RDC-1, ACKR3, ACKR3, atypical chemokine receptor 3, C X C chemokine receptor type 7, C-X-C chemokine receptor type 7, Chemokine (C-X-C motif) receptor 7, Chemokine C X C motif receptor 7, Chemokine orphan receptor 1, CMKOR1, CXC R7, CXC-R7, CXCR 7, CXCR-7, CXCR7, CXCR7, G protein coupled receptor 159, G protein coupled receptor, G protein coupled receptor RDC1 homolog, G-protein coupled receptor 159, G-protein coupled receptor RDC1 homolog, GPR159, GPRN1, RDC 1, RDC-1, RDC1,

Immunogen: recombinant protein

Conjugate: Unconjugated

Modification: Unmodified