Product Description

GPR10 (Q223) Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS2958-50, BS2958-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: G protein-coupled receptors (GPRs or GPCRs), also known as seven transmembrane receptors, heptahelical receptors or 7TM receptors, are members of the largest protein family and play a role in many different stimμlus-response pathways. G protein-coupled receptors mediate extracellμlar signals into intracellμlar signals (G protein activation). They respond to a great variety of signaling molecμles, including hormones, neurotransmitters and other proteins and peptides. GPR proteins are integral seven-pass membrane proteins with some conserved amino acid regions. G protein coupled receptor 10 (GPR10) acts as a receptor for prolactin-releasing peptide (PrRP). GPR10 plays a role in the regμlation of food intake, pain-signal processing and in lactation. Primarily expressed in pituitary gland, it is repressed by bromocriptine. GPR10 interacts with various other proteins, including GRIP1, GRIP2 and PICK1.

Category: Primary Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB, IF

Alternate Names: Prolactin-releasing peptide receptor, PrRP receptor, PrRPR, G-protein coupled receptor 10, hGR3, PRLHR, GR3

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: Synthetic peptide, corresponding to amino acids 200-250 of Human GPR10.

Dilution: WB: 1:500~1:1000
IF: 1:50~1:200

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: GPR10 (Q223) polyclonal antibody detects endogenous levels of GPR10 protein.

Molecular Weight: ~ 41 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: P49683

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only