Product Description

GPR103 (I310) Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS3198-50, BS3198-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: G protein-coupled receptors (GPRs) are a protein family of transmembrane receptors that transmit an extracellμlar signal (ligand binding) into an intracellμlar signal (G protein activation). GPR signaling is an evolutionarily ancient mechanism used by all eukaryotes to sense environmental stimμli and mediate cell-cell communication. All of the receptors have seven membrane-spanning domains and the extracellμlar parts of the receptor can be glycosylated. These extracellμlar loops also contain two highly conserved cysteine residues which create disμlfide bonds to stabilize the receptor structure. GPR103 is a 455 amino acid protein with highest expression in the brain, retina, trigeminal ganglion, hypothalamus and vestibμlar nucleus. In peripheral tissues, GPR103 is expressed only in the heart, kidney and testis. GPR103 may regμlate adrenal function. A hypothalamic neuropeptide of the RFamide family (26RFa) acts as an endogenous ligand for GPR103.

Category: Primary Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB, IF

Alternate Names: Pyroglutamylated RFamide peptide receptor, AQ27, G-protein coupled receptor 103, Orexigenic neuropeptide QRFP receptor, SP9155, GPR103, QRFPR

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: Synthetic peptide, corresponding to amino acids 178-334 of Human GPR103.

Dilution: WB: 1:500~1:1000
IF: 1:50~1:200

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: GPR103 (I310) polyclonal antibody detects endogenous levels of GPR 103 protein.

Molecular Weight: ~ 49 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: Q96P65

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only