GPR116 Polyclonal Antibody
Catalogue Numbers: BS60775-50, BS60775-100
Sizes: 50µl, 100µl
Alternative Name: Probable G-protein coupled receptor 116; GPR116; KIAA0758
Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Swiss-Prot: Q8IZF2
Host: Rabbit
Reactivity: Human, Mouse, Rat
Applications: WB
All Applications: WB: 1:500~1:1000
Background: G protein-coupled receptors (GPRs), also known as seven transmembrane receptors, heptahelical receptors or 7TM receptors, comprise a superfamily of proteins that play a role in many different stimulus-response pathways. G protein coupled receptors translate extracellular signals into intracellular signals (G protein activation) and they respond to a variety of signaling molecules, such as hormones and neurotransmitters. GPR116 (G protein-coupled receptor 116) is a 1,346 amino acid multi-pass membrane protein that contains one SEA domain, one GPS domain and three Ig-like domains and belongs to the GPR family. Existing as a dilsulfide-liked homodimer at the cell surface, GPR116 exists as multiple alternatively spliced isoforms and is thought to play a role in regulating and maintaining proper acid-base balance throughout the cell.
Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: GPR116 polyclonal antibody detects endogenous levels of GPR116 protein.
Bioworld Molecular Weight: ~ 149 kDa
Note: For research use only, not for use in diagnostic procedure.
Extra Notes: Western blot (WB) analysis of GPR116 pAb at 1:500 dilution
Lane 1: 3T3-L1 whole cell lysate(40ug)
Lane 2: PC12 whole cell lysate(40ug)
Lane 3: HEK293T whole cell lysate(40ug)
Lane 4: A549 whole cell lysate(40ug)
Immunogen: A synthetic peptide corresponding to residues in Human GPR116
Conjugate: Unconjugated
Modification: Unmodified