Product Description

GPR143 Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP03696-20, BT-AP03696-50, BT-AP03696-100

Citations, Manuals and MSDS Available upon request.

Background: GPR143 encodes a protein that binds to heterotrimeric G proteins and is targeted to melanosomes in pigment cells. This protein is thought to be involved in intracellular signal transduction mechanisms. Mutations in GPR143 cause ocular albinism type 1, also referred to as Nettleship-Falls type ocular albinism, a severe visual disorder. A related pseudogene has been identified on chromosome Y.

Research Areas: Others

Target Protein: GPR143

Applications: IF, ELISA

Reactivity: Human, Mouse

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: GPR143 Antibody

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Molecular Weight (Da): 43878

UniProt Accession: Human: P51810; Mouse: P70259

Synonyms: GPR143; OA1; G-protein coupled receptor 143; Ocular albinism type 1 protein

GeneID: Human: 4935; Mouse: 18241

Research Use Only