Product Description

GPR158 Polyclonal Antibody

Catalogue Numbers: BS62572-50, BS62572-100

Sizes: 50µl, 100µl

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: Q5T848

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB, IHC, IF

All Applications: WB:1:500~1:1000 IHC:1:50~1:200 IF:1:50~1:200

Background: G-protein coupled receptor 158 (GPR158) is a receptor belonging to the Class C GPCR family. It lacks the extracellular Venus flytrap module characteristic of the known members of that family and instead contains two other elements that are not typical of the class: a calcium-binding EGF-like domain and a leucine repeat region. The mature extracellular domain of human GPR158 contains 393 amino acids (aa) and shares 89% identity with both mouse and rat GPR158. GPR158 is expressed at the highest level in the brain, but also in a variety of other tissues including retina, spleen, liver and lung. GPR158 was originally identified in functional screens linked with biological stress and has been implicated in the osteocalcin effect on cognitive processes in the brain, and glaucoma and cancer in the periphery.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: GPR158 polyclonal antibody detects endogenous levels of GPR158 protein.

Extra Notes: Western blot (WB) analysis of GPR158 polyclonal antibody at 1:500 dilution
LaneA:BV2 whole cell lysate
LaneB:PMVEC whole cell lysate
LaneC:A549 whole cell lysate
LaneD:HepG2 whole cell lysate

Bioworld Molecular Weight: ~ 150 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Name: Probable G-protein coupled receptor 158; GPR158; KIAA1136

Immunogen: Synthetic peptide, corresponding to Human GPR158.

Conjugate: Unconjugated

Modification: Unmodified