Product Description

GPR171 Polyclonal Antibody

Catalogue Numbers: BS5742-50, BS5742-100

Sizes: 50µl, 100µl

Alternative Name: Probable G-protein coupled receptor 171; G-protein coupled receptor H963

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: O14626

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB IF

All Applications: WB: 1:500~1:1000
IF: 1:50~1:200

Background: G protein-coupled receptors (GPRs), also known as seven transmembrane receptors, heptahelical receptors or 7TM receptors, comprise a superfamily of proteins that play a role in many different stimulus-response pathways. GPR signaling is an evolutionarily ancient mechanism used by all eukaryotes to sense environmental stimuli and mediate cell-cell communication. G protein-coupled receptors translate extracellular signals into intracellular signals (G protein activation) and they respond to a variety of signaling molecules, such as hormones and neurotransmitters. G protein-coupled receptors provide attractive targets for drug therapy due to the sheer size and diversity of ligands within this receptor family. GPR171, also designated H963, is a 319 amino acid protein that is structurally related to the purinergic receptors P2Y12, P2Y13 and P2Y14.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: GPR171 polyclonal antibody detects endogenous levels of GPR171 protein.

Bioworld Molecular Weight: ~ 37 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot (WB) analysis of GPR171 polyclonal antibody at 1:500 dilution
Lane 1: HEK293T cell lysate
Lane 2: Mouse liver tissue lysate
Lane 3: Rat liver tissue lysate

Immunogen: Synthetic peptide, corresponding to amino acids 226-271 of Human GPR171.

Conjugate: Unconjugated

Modification: Unmodified