Product Description

GPR68 (R214) Polyclonal Antibody

Catalogue Numbers: BS2315-50, BS2315-100

Sizes: 50µl, 100µl

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: Q15743

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB

All Applications: WB: 1:500~1:1000

Background: G protein-coupled receptors (GPRs), also known as seven transmembrane receptors, heptahelical receptors or 7TM receptors, comprise a superfamily of proteins that play a role in many different stimulus-response pathways. G protein-coupled receptors translate extracellular signals into intracellular signals (G protein activation) and they respond to a variety of signaling molecules, such as hormones and neurotransmitters. GPR68 (G protein-coupled receptor 68), also known as OGR1 (ovarian cancer G-protein coupled receptor 1), is a 365 amino acid multi-pass membrane protein that is expressed in testis, spleen, lung, brain and placenta. Existing as a member of the G protein-coupled receptor family, GPR68 functions as a high affinity receptor for sphingosylphosphorylcholine and is coupled to G proteins that enhance phosphoinositide hydrolysis.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: GPR68 (R214) polyclonal antibody detects endogenous levels of GPR68 protein.

Extra Notes: Western blot (WB) analysis of GPR68 (R214) pAb at 1:500 dilution
Lane1:U-87MG whole cell lysate(40ug)
Lane2:K562 whole cell lysate(40ug)
Lane3:MCF-7 whole cell lysate(40ug)
Lane4:The Lung tissue lysate of Mouse(40ug)
Lane5:The Lung tissue lysate of Rat(40ug)

Bioworld Molecular Weight: ~41 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Name: G protein coupled receptor 68; G-protein coupled receptor 68; GPR 12A; GPR 68; GPR12A; Gpr68; OGR 1; OGR-1; OGR1; OGR1; Ovarian cancer G protein coupled receptor 1; Ovarian cancer G-protein coupled receptor 1; Sphingosylphosphorylcholine receptor

Immunogen: Synthetic peptide, corresponding to amino acids 183-232 of Human GPR68.

Conjugate: Unconjugated

Modification: Unmodified