GPS2 Polyclonal Antibody - RA25513

GPS2 Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA25513-50, RA25513-100

Citations, Manuals and MSDS Available upon request.

Background: G protein pathway suppressor 2 (GPS2) Homo sapiens This gene encodes a protein involved in G protein-mitogen-activated protein kinase (MAPK) signaling cascades. When overexpressed in mammalian cells, this gene could potently suppress a RAS- and MAPK-mediated signal and interfere with JNK activity, suggesting that the function of this gene may be signal repression. The encoded protein is an integral subunit of the NCOR1-HDAC3 (nuclear receptor corepressor 1-histone deacetylase 3) complex, and it was shown that the complex inhibits JNK activation through this subunit and thus could potentially provide an alternative mechanism for hormone-mediated antagonism of AP1 (activator protein 1) function. [provided by RefSeq, Jul 2008],

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage Instructions: -20°C/1 year

Recommended dilutions: Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.

Alternative Names: GPS2; G protein pathway suppressor 2; GPS-2

Applications: WB; ELISA

Species Cross-Reactivity: Human; Mouse; Rat

GeneID (Human): 2874

Protein MW (KDa): 40

SWISS: Q13227

Source: Rabbit

Research Use Only