GPT2 Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A23670-20, A23670-100
Citations, Manuals and MSDS Available upon request.
Background: This gene encodes a mitochondrial alanine transaminase, a pyridoxal enzyme that catalyzes the reversible transamination between alanine and 2-oxoglutarate to generate pyruvate and glutamate. Alanine transaminases play roles in gluconeogenesis and amino acid metabolism in many tissues including skeletal muscle, kidney, and liver. Activating transcription factor 4 upregulates this gene under metabolic stress conditions in hepatocyte cell lines. A loss of function mutation in this gene has been associated with developmental encephalopathy. Alternative splicing results in multiple transcript variants.
Category: Polyclonal Antibodies
Applications: WB, ELISA
Cross-reactivity: Human
Protein Weight: 58kDa
Observed Molecular Weight: 58 kDa
Immunogen: Recombinant protein (or fragment) .
Species: Human
GeneID: 84706
SWISS: Q8TD30
Alternate Names: ALT2; GPT 2; MRT49; NEDSPM; GPT2
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Recommended Dilutions: WB, 1:500 - 1:1000 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Cancer, Endocrine Metabolism, Amino acid metabolism.
NCBI Alias: GPT2
Research Use Only