GPT2 Rabbit pAb
Sizes: 20µl, 100µl
Catalogue Numbers: A23670-20, A23670-100
Citations, Manuals and SDS Available upon request.
Background: This gene encodes a mitochondrial alanine transaminase, a pyridoxal enzyme that catalyzes the reversible transamination between alanine and 2-oxoglutarate to generate pyruvate and glutamate. Alanine transaminases play roles in gluconeogenesis and amino acid metabolism in many tissues including skeletal muscle, kidney, and liver. Activating transcription factor 4 upregulates this gene under metabolic stress conditions in hepatocyte cell lines. A loss of function mutation in this gene has been associated with developmental encephalopathy. Alternative splicing results in multiple transcript variants.
Synonyms: ALT2; GPT 2; MRT49; NEDSPM; GPT2
GeneID: 84706
Swiss-Prot: Q8TD30
Reactivity: Human
Tested Applications: ELISA, WB
Calculated Molecular Weight: 58kDa
Observed Molecular Weight: 58 kDa
Immunogen: Recombinant protein of human GPT2.
Immunogen Species: Human
Host: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage Buffer: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.05% proclin300, 50% glycerol, pH7.3.
Research Areas: Cancer, Endocrine Metabolism, Amino acid metabolism
Recommended Dilutions: WB: 1:500 - 1:1000
Modifications: Unmodified
Conjugate: Unconjugated
Cellular Location: Mitochondrial Matrix,
Positive Samples: HepG2
Keywords: 84706, sc-46352, sc-46349, sc-46350, sc-46351, sc-66914, AAT2, Alanine aminotransferase 2, ALT2, GPT 2, GPT2, MRT49, glutamic--pyruvic transaminase 2, alanine aminotransferase 2, glutamate pyruvate transaminase 2, glutamic pyruvate transaminase (alanine aminotransferase) 2, glutamic pyruvate transaminase 2, glutamic--alanine transaminase 2, Q8TD30, Glutamic--Pyruvic Transaminase 2, Glutamate Pyruvate Transaminase 2, Glutamic--Alanine Transaminase 2, Glutamic Pyruvate Transaminase 2, Alanine Aminotransferase 2, Glutamic Pyruvate Transaminase (Alanine Aminotransferase) 2, EC 2.6.1.2, sc46352, sc 46352, sc46349, sc 46349, sc46350, sc 46350, sc46351, sc 46351, sc66914, sc 66914
Symbol: GPT2
Category: Polyclonal Antibodies
Research Use Only