GRAF Polyclonal Antibody-BS65676

GRAF Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BS65676-50, BS65676-100

Product: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Swiss-Prot: Q9UNA1

Host: Rabbit

Reactivity: Human, Mouse, Rat,Chicken,Dog, Pig, Cow, Rabbit, Sheep,

Applications: WB

All Applications: WB=1:500-2000

Background: Cellular signaling by G-proteins is down-regulated by GTPase-activating proteins (GAPs), which increase the rate of GTP hydroylsis. The GTPase regulator associated with focal adhesion kinase (GRAF) has GAP activity toward Rho A and Cdc42, but not Rac1. GRAF is ubiquitously expressed with high levels in heart and brain. Expression of GRAF causes clearing of stress fibers and formation of long actin based filopodial-like extensions. Fusion of MLL with GRAF, MLL/GRAF, is included in a rare genetic subgroup of acute myeloid leukemia (AML) cases.

Purification and Purity: affinity purified by Protein A

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: GRAF Polyclonal Antibody detects endogenous levels of GRAF protein.

Bioworld Molecular Weight: 38 kD

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Sample:
Cerebrum(Rat) Lysate at 40 ug
Cerebrum(Mouse) Lysate at 40 ug
Cerebellum(Rat) Lysate at 40 ug
HepG2(Human) Cell Lysate at 30 ug
Kidney(Rat) Lysate at 40 ug
Kidney(Mouse) Lysate at 40 ug
A549(Human) Cell Lysate at 30 ug
A431(Human) Cell Lysate at 30 ug
HL60(Human) Cell Lysate at 30 ug
U937(Human) Cell Lysate at 30 ug
Cerebellum(Mouse) Lysate at 40 ug
Primary: Anti-GRAF at 1/1000 dilution

Alternative Name: arhgap 26; ARHGAP26; FLJ42530; GRAF; GRAF1; GTPase regulator associated with focal adhesion kinase; GTPase regulator associated with focal adhesion kinase pp125(FAK); KIAA0621; oligophrenin 1 like protein; Oligophrenin-1-like protein; oligophrenin1like protein; OPHN1L; OPHN1L1; RHG26_HUMAN; Rho GTPase activating protein 26; Rho GTPase activating protein26; Rho GTPase-activating protein 26; Rho-type GTPase-activating protein 26.

Immunogen: KLH conjugated synthetic peptide derived from human GRAF1

Conjugate: Unconjugated

Modification: Unmodified