Product Description

GRAF Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS65676-50, BS65676-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Cellμlar signaling by G-proteins is down-regμlated by GTPase-activating proteins (GAPs), which increase the rate of GTP hydroylsis. The GTPase regμlator associated with focal adhesion kinase (GRAF) has GAP activity toward Rho A and Cdc42, but not Rac1. GRAF is ubiquitously expressed with high levels in heart and brain. Expression of GRAF causes clearing of stress fibers and formation of long actin based filopodial-like extensions. Fusion of MLL with GRAF, MLL/GRAF, is included in a rare genetic subgroup of acute myeloid leukemia (AML) cases.

Category: Primary Antibody

Reactivity: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Rabbit, Sheep

Host: Rabbit

Applications: WB

Alternate Names: arhgap 26, ARHGAP26, FLJ42530, GRAF, GRAF1, GTPase regμlator associated with focal adhesion kinase, GTPase regμlator associated with focal adhesion kinase pp125(FAK), KIAA0621, oligophrenin 1 like protein, Oligophrenin-1-like protein, oligophrenin1like protein, OPHN1L, OPHN1L1, RHG26_HUMAN, Rho GTPase activating protein 26, Rho GTPase activating protein26, Rho GTPase-activating protein 26, Rho-type GTPase-activating protein 26.

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: KLH conjugated synthetic peptide derived from human GRAF1

Dilution: WB=1:500-2000

Purification: affinity purified by Protein A

Specificity: GRAF Polyclonal Antibody detects endogenous levels of GRAF protein.

Molecular Weight: 38 kD

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: Q9UNA1

Product: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Research Use Only