Product Description

Granμlin Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS7852-50, BS7852-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Granμlins are a family of secreted, glycosylated peptides that are cleaved from a single precursor protein with 7.5 repeats of a highly conserved 12-cysteine granμlin/epithelin motif. The 88 kDa precursor protein, progranμlin, is also called proepithelin and PC cell-derived growth factor. Cleavage of the signal peptide produces mature granμlin which can be further cleaved into a variety of active, 6 kDa peptides. These smaller cleavage products are named granμlin A, granμlin B, granμlin C, etc. Epithelins 1 and 2 are synonymous with granμlins A and B, respectively. Both the peptides and intact granμlin protein regμlate cell growth. However, different members of the granμlin protein family may act as inhibitors, stimμlators, or have dual actions on cell growth. Granμlin family members are important in normal development, wound healing, and tumorigenesis.

Category: Primary Antibody

Reactivity: Human, Mouse

Host: Rabbit

Applications: WB, IF/ICC

Alternate Names: GRN, CLN11, GEP, GP88, PCDGF, PEPI, PGRN, granμlins

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: Recombinant fusion protein of human Granμlin(NP_002078.1).

Dilution: WB, 1:500 - 1:2000 IF/ICC, 1:50 - 1:200

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: Polyclonal Antibodies

Molecular Weight: 88KDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: P28799

Product: 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only