Granzyme B Mouse Monoclonal Antibody (PT0564) - RA11307

Granzyme B Mouse Monoclonal Antibody (PT0564)

Size: 50μL, 100μL

Catalogue Numbers: RA11307-50, RA11307-100

Citations, Manuals and MSDS Available upon request.

Background: granzyme B (GZMB) Homo sapiens This gene encodes a member of the granzyme subfamily of proteins, part of the peptidase S1 family of serine proteases. The encoded preproprotein is secreted by natural killer (NK) cells and cytotoxic T lymphocytes (CTLs) and proteolytically processed to generate the active protease, which induces target cell apoptosis. This protein also processes cytokines and degrades extracellular matrix proteins, and these roles are implicated in chronic inflammation and wound healing. Expression of this gene may be elevated in human patients with cardiac fibrosis. [provided by RefSeq, Sep 2016],

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage Instructions: -20°C/1 year

Applications: IHC-p; IF (paraffin section)

Species Cross-Reactivity: Human

Protein MW (KDa): 40

SWISS: P10144

Source: Mouse

Research Use Only