Product Description

Granzyme B Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA21017-50, RA21017-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: granzyme B (GZMB) Homo sapiens This gene encodes a member of the granzyme subfamily of proteins, part of the peptidase S1 family of serine proteases. The encoded preproprotein is secreted by natural killer (NK) cells and cytotoxic T lymphocytes (CTLs) and proteolytically processed to generate the active protease, which induces target cell apoptosis. This protein also processes cytokines and degrades extracellular matrix proteins, and these roles are implicated in chronic inflammation and wound healing. Expression of this gene may be elevated in human patients with cardiac fibrosis. [provided by RefSeq, Sep 2016],

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB, IHC-p, IF (paraffin section), ELISA

Alternate Names: Granzyme B (EC 3.4.21.79;C11;CTLA-1;Cathepsin G-like 1;CTSGL1;Cytotoxic T-lymphocyte proteinase 2;Lymphocyte protease;Fragmentin-2;Granzyme-2;Human lymphocyte protein;HLP;SECT;T-cell serine protease 1-3E)

Clonality: Polyclonal

Dilution: IHC-p: 100-300.WB 1:500-2000, ELISA 1:10000-20000

Molecular Weight: 40

Protein Molecular Weight (kDa): 40

Storage: -20°C/1 year

Human Gene ID: 3002

Human SwissProt Number: P10144

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Research Use Only