Granzyme B Rabbit Monoclonal Antibody-BS40492

Granzyme B Rabbit Monoclonal Antibody

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.

Catalogue Numbers: BS40492-50, BS40492-100

Sizes: 50µl, 100µl

Swiss-Prot: P10144

Host: Rabbit

Reactivity: Human

Applications: IHC ICC/IF IP

Background: This enzyme is necessary for target cell lysis in cell-mediated immune responses. It cleaves after Asp. Seems to be linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis execution. Cleaves caspase-3, -7, -9 and 10 to give rise to active enzymes mediating apoptosis.

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.

Purification and Purity: Affinity-chromatography

Specificity: Granzyme B Antibody detects endogenous levels of total Granzyme B

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Immunohistochemical analysis of paraffin-embedded human T cell lymphoma, using Granzyme B Antibody.

Bioworld Molecular Weight: 38kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Alternative Name: Granzyme B; Cathepsin G-like 1; CTSGL1; Lymphocyte protease; Fragmentin-2; Granzyme-2; Human lymphocyte protein; SECT; GZMB; CGL1; CSPB; CTLA1, GRB;

Immunogen: A synthesized peptide derived from human Granzyme B

Conjugate: Unconjugated

Modification: Unmodified