Product Description

Granzyme B Rabbit Monoclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS40492-50, BS40492-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: This enzyme is necessary for target cell lysis in cell-mediated immune responses. It cleaves after Asp. Seems to be linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis execution. Cleaves caspase-3, -7, -9 and 10 to give rise to active enzymes mediating apoptosis.

Category: Primary Antibody

Reactivity: Human

Host: Rabbit

Applications: IHC, ICC/IF, IP

Alternate Names: Granzyme B, Cathepsin G-like 1, CTSGL1, Lymphocyte protease, Fragmentin-2, Granzyme-2, Human lymphocyte protein, SECT, GZMB, CGL1, CSPB, CTLA1, GRB,

Clonality: Monoclonal

Conjugate: Unconjugated

Modification: Unmodified

Immunogen: A synthesized peptide derived from human Granzyme B

Dilution: IHC 1:50~1:200 ICC/IF 1:50~1:200 IP 1:50

Purification: Affinity-chromatography

Specificity: Granzyme B Antibody detects endogenous levels of total Granzyme B

Molecular Weight: 38kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: P10144

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.

Research Use Only