Granzyme B Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A28337-20, A28337-100
Citations, Manuals and MSDS Available upon request.
Background: This gene encodes a member of the granzyme subfamily of proteins, part of the peptidase S1 family of serine proteases. The encoded preproprotein is secreted by natural killer (NK) cells and cytotoxic T lymphocytes (CTLs) and proteolytically processed to generate the active protease, which induces target cell apoptosis. This protein also processes cytokines and degrades extracellular matrix proteins, and these roles are implicated in chronic inflammation and wound healing. Mice lacking a functional copy of this gene exhibit impaired immune cell-mediated cytolysis.
Category: Polyclonal Antibodies
Applications: WB, ELISA
Cross-reactivity: Mouse
Protein Weight: 27 kDa
Observed Molecular Weight: 30 kDa
Immunogen: Synthetic peptide .
Species: Mouse
GeneID: 14939
SWISS: P04187
Alternate Names: GZB; CCP1; Ctla1; Ctla-1; CCP-1/C11
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.09% Sodium azide, 50% glycerol, pH 7.3.
Recommended Dilutions: WB, 1:1000 - 1:3000 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements. For high-ratio antibody dilutions (≥1:10000) ，a sequential dilution method is strongly recommended to ensure measurement accuracy.
Research Areas: Immunology & Infectious Disease
NCBI Alias: Gzmb
Research Use Only