Gremlin-2 Polyclonal Antibody
Sizes: 50μL, 100μL
Catalogue Numbers: RA25539-50, RA25539-100
Citations, Manuals and MSDS Available upon request.
Background: gremlin 2, DAN family BMP antagonist (GREM2) Homo sapiens This gene encodes a member of the BMP (bone morphogenic protein) antagonist family. Like BMPs, BMP antagonists contain cystine knots and typically form homo- and heterodimers. The CAN (cerberus and dan) subfamily of BMP antagonists, to which this gene belongs, is characterized by a C-terminal cystine knot with an eight-membered ring. The antagonistic effect of the secreted glycosylated protein encoded by this gene is likely due to its direct binding to BMP proteins. As an antagonist of BMP, this gene may play a role in regulating organogenesis, body patterning, and tissue differentiation. [provided by RefSeq, Jul 2008],
Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Storage Instructions: -20°C/1 year
Recommended dilutions: WB 1:500-2000,IHC-p 1:500-200, ELISA 1:10000-20000
Alternative Names: Gremlin-2 (Cysteine knot superfamily 1, BMP antagonist 2;DAN domain family member 3;Protein related to DAN and cerberus)
Applications: WB; IHC-p; IF (paraffin section) ; ELISA
Species Cross-Reactivity: Human; Mouse
GeneID (Human): 64388
Protein MW (KDa): 19
SWISS: Q9H772
Source: Rabbit
Research Use Only