Product Description

GRID1 Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS65713-50, BS65713-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Glutamate receptors mediate most excitatory neurotransmissions in the brain and play an important role in neural plasticity, neural development and neurodegeneration. Ionotropic glutamate receptors are divided into two categories, namely NMDA receptors and kainate/AMPA receptors, both of which contain glutamate-gated, cation-specific ion channels. Kainate/AMPA receptors consist of seven structurally related subunits, designated GluR-1 to -7, and are primarily responsible for fast excitatory neurotransmissions carried out by glutamate. GluR-delta 1 (Glutamate receptor delta-1 subunit), also known as GRID1, is a mμlti-pass membrane protein that belongs to the kainate/AMPA receptor family and is expressed primarily in the brain. Localized to the cell junction and the postsynaptic cell membrane, GluR-delta 1 functions as a glutamate receptor that regμlates synaptic transmissions in the central nervous system (CNS) and is thought to play an important role in synaptic plasticity. Defects in the gene encoding GluR-delta 1 are associated with schizophrenia, a chronic and severe brain disorder.

Category: Primary Antibody

Reactivity: Human, Mouse, Rat, Chicken, Dog, Cow, Horse, Sheep

Host: Rabbit

Applications: FCM

Alternate Names: GluR delta 1, GluR delta 1 subunit, GluR delta-1 subunit, Glutamate receptor delta 1 subunit, Glutamate receptor delta-1 subunit, Glutamate receptor ionotropic delta 1, GRID 1, Grid1, GRID1_HUMAN, KIAA1220. 

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: KLH conjugated synthetic peptide derived from human GRID1:501-600/1009

Dilution: Flow-Cyt=1ug/test

Purification: affinity purified by Protein A

Specificity: GRID1 Polyclonal Antibody detects endogenous levels of GRID1 protein.

Molecular Weight: 110kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: Q9μlK0

Product: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Research Use Only