GRIK2 (GluR6) Polyclonal Antibody - RA25545

GRIK2 (GluR6) Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA25545-50, RA25545-100

Citations, Manuals and MSDS Available upon request.

Background: glutamate ionotropic receptor kainate type subunit 2 (GRIK2) Homo sapiens Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to the kainate family of glutamate receptors, which are composed of four subunits and function as ligand-activated ion channels. The subunit encoded by this gene is subject to RNA editing at multiple sites within the first and second transmembrane domains, which is thought to alter the structure and function of the receptor complex. Alternatively spliced transcript variants encoding different isoforms have also been described for this gene. Mutations in this gene have been associated with autosomal recessive mental retardation. [provided by RefSeq, Jul 2008],

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage Instructions: -20°C/1 year

Recommended dilutions: IHC 1:100-200

Alternative Names: Glutamate receptor, ionotropic kainate 2 (Excitatory amino acid receptor 4;EAA4;Glutamate receptor 6;GluR-6;GluR6)

Applications: IHC-p; IF (paraffin section)

Species Cross-Reactivity: Human

GeneID (Human): 2898

Protein MW (KDa): 103

SWISS: Q13002

Source: Rabbit

Research Use Only