Product Description

GRIK2 Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-60513-60, E-AB-60513-120, E-AB-60513-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: GRIK2

Target Synonym: GRIK2; EAA4; GLR6; GLUK6; GLUR6; GluK2; MRT6; kainate 2

Research Areas: Cancer,Neuroscience

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human, Mouse

Application: WB

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: Q13002

Background: Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to the kainate family of glutamate receptors, which are composed of four subunits and function as ligand-activated ion channels. The subunit encoded by this gene is subject to RNA editing at multiple sites within the first and second transmembrane domains, which is thought to alter the structure and function of the receptor complex. Alternatively spliced transcript variants encoding different isoforms have also been described for this gene. Mutations in this gene have been associated with autosomal recessive mental retardation.

Concentration: 1 mg/mL

Immunogen: Recombinant fusion protein of human GRIK2

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification Method: Affinity purification

Dilution: WB 1:500-1:2000

Calculated MW: 66kDa/77kDa/93kDa/97kDa/100kDa/102kDa

Observed MW: 115kDa

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only