GRK1/2 (Phospho-Tyr13) Rabbit Polyclonal Antibody - RA36900

GRK1/2 (Phospho-Tyr13) Rabbit Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA36900-50, RA36900-100

Citations, Manuals and MSDS Available upon request.

Background: G protein-coupled receptor kinase 2 (GRK2) Homo sapiens The product of this gene phosphorylates the beta-2-adrenergic receptor and appears to mediate agonist-specific desensitization observed at high agonist concentrations. This protein is an ubiquitous cytosolic enzyme that specifically phosphorylates the activated form of the beta-adrenergic and related G-protein-coupled receptors. Abnormal coupling of beta-adrenergic receptor to G protein is involved in the pathogenesis of the failing heart. [provided by RefSeq, Jul 2008],

Condition: Liquid in PBS containing 50% glycerol, and 0.216% sodium azide.

Storage Instructions: -20°C/1 year

Recommended dilutions: WB 1:500-2000

Alternative Names: Beta-adrenergic receptor kinase 1 (Beta-ARK-1) (EC 2.7.11.15) (G-protein coupled receptor kinase 2)

Applications: WB

Species Cross-Reactivity: Human; Mouse; Rat

GeneID (Human): 156

SWISS: P25098

Source: Rabbit

Research Use Only