Product Description

GRK2 Monoclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: MB12048-50, MB12048-100

Product: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Swiss-Prot: P25098

Host: Rabbit

Reactivity: Human

Applications: WB,IP

All Applications: WB: 1/500-1/1000 IP: 1/20

Background: GRK2 kinase activity and cellular localization are tightly regulated by interactions with activated receptors, G-beta and G-gamma subunits, adaptor proteins, phospholipids, caveolin and calmodulin, as well as by phosphorylation. PKC phosphorylation enhances GRK2 activity by promoting its membrane localization and by abolishing the inhibitory association of calmodulin.

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of GRK2 in Hela, A549, HL-60, U2OSLysates using GRK2 antibody.

Bioworld Molecular Weight: Calculated MW: 80 kDa; Observed MW: 80 kDa

Specificity: IgG

Alternative Name: GRK2; BARK1; FLJ16718; BETA-ARK1; ADRBK1

Immunogen: A synthetic peptide of human GRK2

Conjugate: Unconjugated

Modification: Unmodified