GRK2 (Phospho-Tyr86) Polyclonal Antibody - RA25568

GRK2 (Phospho-Tyr86) Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA25568-50, RA25568-100

Citations, Manuals and MSDS Available upon request.

Background: G protein-coupled receptor kinase 2 (GRK2) Homo sapiens The product of this gene phosphorylates the beta-2-adrenergic receptor and appears to mediate agonist-specific desensitization observed at high agonist concentrations. This protein is an ubiquitous cytosolic enzyme that specifically phosphorylates the activated form of the beta-adrenergic and related G-protein-coupled receptors. Abnormal coupling of beta-adrenergic receptor to G protein is involved in the pathogenesis of the failing heart. [provided by RefSeq, Jul 2008],

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage Instructions: -20°C/1 year

Recommended dilutions: IHC-p 1:50-200, WB 1:500-2000

Alternative Names: Beta-adrenergic receptor kinase 1 (Beta-ARK-1;EC 2.7.11.15;G-protein coupled receptor kinase 2)

Applications: IHC-p; IF (paraffin section) ; WB

Species Cross-Reactivity: Human; Mouse; Rat

GeneID (Human): 156

Protein MW (KDa): 75

SWISS: P25098

Source: Rabbit

Research Use Only