Product Description

GRK2 (Phospho-Tyr86) Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA25568-50, RA25568-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: G protein-coupled receptor kinase 2 (GRK2) Homo sapiens The product of this gene phosphorylates the beta-2-adrenergic receptor and appears to mediate agonist-specific desensitization observed at high agonist concentrations. This protein is an ubiquitous cytosolic enzyme that specifically phosphorylates the activated form of the beta-adrenergic and related G-protein-coupled receptors. Abnormal coupling of beta-adrenergic receptor to G protein is involved in the pathogenesis of the failing heart. [provided by RefSeq, Jul 2008],

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: IHC-p, IF (paraffin section), WB

Alternate Names: Beta-adrenergic receptor kinase 1 (Beta-ARK-1;EC 2.7.11.15;G-protein coupled receptor kinase 2)

Clonality: Polyclonal

Dilution: IHC-p 1:50-200, WB 1:500-2000

Molecular Weight: 75

Protein Molecular Weight (kDa): 75

Storage: -20°C/1 year

Human Gene ID: 156

Human SwissProt Number: P25098

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Research Use Only