Growth Hormone Receptor Polyclonal Antibody
Product: Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Sizes: 50µl, 100µl
Catalogue Numbers: BZ16842-50, BZ16842-100
Swiss-Prot: P10912
Host: Rabbit
Reactivity: Human, Mouse, Rat
Applications: WB, ICC/IF, FC
All Applications: WB: 1/500-1/1000 IF: 1/50-1/200 FC: 1/50-1/100
Background: Receptor for pituitary gland growth hormone involved in regulating postnatal body growth. On ligand binding, couples to the JAK2/STAT5 pathway. The soluble form (GHBP) acts as a reservoir of growth hormone in plasma and may be a modulator/inhibitor of GH signaling.
Isoform 2 up-regulates the production of GHBP and acts as a negative inhibitor of GH signaling.
Purification and Purity: Affinity Purified
Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: IgG
Calculated MW: 72 kDa; Observed MW: 140 kDa
Note: For research use only, not for use in diagnostic procedure.
Extra Notes: Western blot analysis of Growth hormone receptor in MCF-7 lysates; mouse brain lysates using Growth Hormone Receptor antibody.
Alternative Name: GHR; Growth hormone receptor; GH receptor; Somatotropin receptor
Immunogen: A synthesized peptide derived from human Growth hormone receptor
Conjugate: Unconjugated
Modification: Unmodified