GRP78 BiP rabbit pAb - ES8607

GRP78 BiP rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES8607-50, ES8607-100

Citations, Manuals and MSDS Available upon request.

Background: The protein encoded by this gene is a member of the heat shock protein 70 (HSP70) family. It is localized in the lumen of the endoplasmic reticulum (ER), and is involved in the folding and assembly of proteins in the ER. As this protein interacts with many ER proteins, it may play a key role in monitoring protein transport through the cell.[provided by RefSeq, Sep 2010],

Alternate Name: 78 kDa glucose-regulated protein (GRP-78) (Endoplasmic reticulum lumenal Ca (2+)-binding protein grp78) (Heat shock 70 kDa protein 5) (Immunoglobulin heavy chain-binding protein) (BiP)

Source: Rabbit

Applications: WB; IHC; IF; ELISA

Dilution: Western Blot: 1/500 - 1/2000.IHC-p/f:1:50-300. ELISA 1:10000-20000

Reactivity: Human; Mouse; Rat; Fish

Immunogen: Synthetic peptide from human protein at AA range: 505-570

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 78kD

Human Gene ID: 3309

Human SWISS Prot NO: P11021

Subcellular Location: Endoplasmic reticulum lumen. Melanosome. Cytoplasm. Cell surface. Identified by mass spectrometry in melanosome fractions from stage I to stage IV (PubMed:12643545). Localizes to the cell surface of epithelial cells in response to high levels of free iron (PubMed:20484814, PubMed:24355926, PubMed:27159390).

Research Use Only