Product Description

GRTP1 Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS62384-50, BS62384-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Pituitary growth hormone (GH), also designated somatotropin, plays a crucial role in stimμlating and controlling the growth, metabolism and differentiation of many mammalian cell types by modμlating the synthesis of mμltiple mRNA species. These effects are mediated by the binding of GH to its membranebound receptor, GHR, and involve a phosphorylation cascade that resμlts in the modμlation of numerous signaling pathways. GRTP1 (growth hormoneregμlated TBC protein 1), also designated TBC1 domain family member 6, is a 336 amino acid protein with expression modμlated by growth hormone. The TBC1 domain of GRTP1 is a region that is notably conserved among GTPaseactivating proteins, which characteristically play a role in the cell cycle and mitosis coordination. Interestingly, expression of GRTP1 is significantly upregμlated in post-puberty testis and then maintained in the adμlt, suggesting that the germ cell may be the major site of GRTP1 function. There are two isoforms of GRTP1, which are a resμlt of alternative splicing events.

Category: Primary Antibody

Reactivity: Human, Rat, Mouse

Host: Rabbit

Applications: WB, IHC

Alternate Names: Growth hormone-regμlated TBC protein 1, TBC1 domain family member 6, GRTP1, TBC1D6

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: Synthetic peptide, corresponding to Human GRTP1.

Dilution: WB:1:500~1:1000 IHC:1:50~1:200

Purification: The protein was purified from E.coli and the purity is > 95% (by SDS-PAGE).

Specificity: GRTP1 polyclonal antibody detects endogenous levels of GRTP1 protein.

Molecular Weight: ~ 38 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: Q5TC63

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.4.

Research Use Only