GSC2 Polyclonal Antibody - RA25583

GSC2 Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA25583-50, RA25583-100

Citations, Manuals and MSDS Available upon request.

Background: goosecoid homeobox 2 (GSC2) Homo sapiens Goosecoidlike (GSCL), a homeodomain-containing gene, resides in the critical region for VCFS/DGS on 22q11. Velocardiofacial syndrome (VCFS) is a developmental disorder characterized by conotruncal heart defects, craniofacial anomalies, and learning disabilities. VCFS is phenotypically related to DiGeorge syndrome (DGS) and both syndromes are associated with hemizygous 22q11 deletions. Because many of the tissues and structures affected in VCFS/DGS derive from the pharyngeal arches of the developing embryo, it is believed that haploinsufficiency of a gene involved in embryonic development may be responsible for its etiology. The gene is expressed in a limited number of adult tissues, as well as in early human development. [provided by RefSeq, Jul 2008],

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage Instructions: -20°C/1 year

Recommended dilutions: Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.

Alternative Names: GSC2; GSCL; Homeobox protein goosecoid-2; GSC-2; Homeobox protein goosecoid-like; GSC-L

Applications: WB; ELISA

Species Cross-Reactivity: Human; Mouse

GeneID (Human): 2928

Protein MW (KDa): 25

SWISS: O15499

Source: Rabbit

Research Use Only