Product Description

Gsh1 Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS65696-50, BS65696-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Growth hormone-releasing hormone (GHRH) stimμlates secretion and synthesis of growth hormone (GH), causes somatotroph proliferation and may have direct actions in fetal/placental development, reproduction and immune function. It exerts its action through high-affinity GHRH receptors present in the anterior pituitary. GSH-1 (GS homeobox 1) is a 264 amino acid hypothalamic nuclear protein that functions as a transcription factor responsible for maintaining GHRH expression as well as playing an important role in pituitary development. Coexpression of CBP leads to significantly enhanced GSH-1-induced GHRH expression, which suggest that CBP may function as a co-activator. Knockdown of GSH-1 mRNA in mice causes a dwarf phenotype, which suggests that certain cases of familial dwarfism may be caused by a mutation of the GSH-1 gene.

Category: Primary Antibody

Reactivity: Human, Mouse, Rat, Dog, Pig, Sheep

Host: Rabbit

Applications: WB

Alternate Names: GS homeo box protein 1, GS homeobox 1, GSH1, GSX1, GSX1_HUMAN, Homeobox protein GSH-1 , Homeobox protein Gsh1.

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: KLH conjugated synthetic peptide derived from human Gsh1

Dilution: WB=1:500-2000

Purification: affinity purified by Protein A

Specificity: Gsh1 Polyclonal Antibody detects endogenous levels of Gsh1 protein.

Molecular Weight: 30 kD

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: Q9H4S2

Product: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Research Use Only