GSK3 alpha/beta Monoclonal Antibody-MB10403

GSK3 alpha/beta Monoclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: MB10403-50, MB10403-100

Product: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Swiss-Prot: P49840

Host: Rabbit

Reactivity: Human, Rat,Hamster

Applications: WB

All Applications: WB: 1/500-1/1000

Background: GSK3A a proline-directed protein kinase of the GSK family. Implicated in the control of several regulatory proteins including glycogen synthase, Myb, and c-Jun. GSK3 and GSK3 have similar functions. GSK3 phophorylates tau, the principal component of neurofibrillary tangles in Alzheimer disease and is required for maximal production of amyloid plaque peptides by secretase.

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of GSK3 alpha + beta in Jurkat, rat Brain, C6, CHO-K1, HelaLysates using GSK3 alpha/beta antibody.

Bioworld Molecular Weight: Calculated MW: 51 kDa; Observed MW: 51,47 kDa

Specificity: IgG

Alternative Name: Serine/threonine-protein kinase GSK3A

Immunogen: A synthetic peptide of human GSK3 alpha

Conjugate: Unconjugated

Modification: Unmodified