GSK3 beta Monoclonal Antibody-MB3162

GSK3 beta Monoclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: MB3162-50, MB3162-100

Product: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Swiss-Prot: P49841

Host: Mouse

Reactivity: Human, Mouse, Rat

Applications: WB, IHC-P, FC

All Applications: WB: 1/500-1/1000 IHC: 1/50-1/100 FC: 1/50-1/100

Background: Glycogen synthase kinase-3 (GSK3) is a proline-directed serine-threonine kinase that was initially identified as a phosphorylating and inactivating glycogen synthase .GSK3B is involved in energy metabolism, neuronal cell development, and body pattern formation.In skeletal muscle, it contributes to insulin regulation of glycogen synthesis by phosphorylating and inhibiting GYS1 activity and hence glycogen synthesis.

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: IgG1

Bioworld Molecular Weight: Calculated MW: 47 kDa; Observed MW: 47 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Flow Cytometry analysis of NIH/3T3 cells stained with GSK3B antibody and negative control., Immunohistochemistry analysis of paraffin-embedded rectum cancer tissues using GSK3B antibody with DAB staining.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval., Immunohistochemistry analysis of paraffin-embedded esophageal cancer tissues using GSK3B antibody with DAB staining.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval., Western blot analysis of GSK3B antibody in Hela, 3T3, C6, rat Brain lysates using GSK3B antibody.

Alternative Name: GSK3B; Glycogen synthase kinase-3 beta; GSK-3 beta; Serine/threonine-protein kinase GSK3B

Immunogen: Purified recombinant fragment of human GSK3B (AA: 2-159) expressed in E. Coli.

Conjugate: Unconjugated

Modification: Unmodified