Product Description

GST3 Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BS90608-50, BS90608-100

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: P09211(Human) P19157(Mouse)

Host: Rabbit

Reactivity: Human, Mouse

Applications: WB, ICC IF, IHC

All Applications: WB:1:500-1:1,000
ICC:1:50-1:200
IHC:1:50-1:200

Background: Glutathione S-transferases (GSTs) function in the metabolic detoxification of various environmental carcinogens and lipid hydroperoxides. In response to oxidative stress, upregulation of the GST family member GSTP1 occurs, consistent with this function. Furthermore, the GSTP1 gene is subject to CpG island hypermethylation, a state that correlates with human prostatic carcinogenesis. GSTP1 gene hypermethylation can be detected in urine, ejaculate and plasma from men with prostate cancer, potentially making GSTP1 a useful biomarker for prostate cancer screening.

Purification and Purity: ProA affinity purified

Storage and Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Specificity: GST3 polyclonal antibody detects endogenous levels of GST3 protein.

Bioworld Molecular Weight: 23 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of GST3 on mouse liver tissue (1) and A549 cell (2) lysate using anti-GST3 antibody at 1/500 dilution., ICC staining GST3 in A431 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.

Alternative Name: GSTP1, FAEES3, GST3, Deafness, Deafness X-linked 7, DFN7, FAEES3, Fatty Acid Ethyl Ester Synthase III, Glutathione S Transferase 3, Glutathione S Transferase Pi, Glutathione S-transferase P, Glutathione S-transferase pi 1, GST class-pi, GST3, GSTP, Gstp1, GSTP1-1, GSTP1, PI, X linked 7,

Immunogen: Recombinant protein

Conjugate: Unconjugated

Modification: Unmodified