Product Description

GSTA3 Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS65569-50, BS65569-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. These enzymes are involved in cellμlar defense against toxic, carcinogenic, and pharmacologically active electrophilic compounds. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. Glutathione S-transferase A3 (GSTA3) belongs to the alpha class genes that are located in a cluster mapped to chromosome 6. Genes of the alpha class are highly related and encode enzymes with glutathione peroxidase activity. However, during evolution, this alpha class gene diverged accumμlating mutations in the active site that resμlted in differences in substrate specificity and catalytic activity. GSTA3 catalyzes the double bond isomerization of precursors for progesterone and testosterone during the biosynthesis of steroid hormones.

Category: Primary Antibody

Reactivity: Rat

Host: Rabbit

Applications: WB

Alternate Names: Glutathione S alkyltransferase A3, Glutathione S aralkyltransferase A3, Glutathione S aryltransferase A3, Glutathione S transferase A3 3, Glutathione S transferase A3, Glutathione S transferase alpha 3, Glutathione transferase alpha 3, GST class alpha, GST class alpha member 3, GSTA 3, GSTA3 3, GTA 3, GTA3, GTA-3, MGC22232, S (hydroxyalkyl)glutathione lyase A3, GSTA3_HUMAN.

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: KLH conjugated synthetic peptide derived from mouse GSTA3:51-150/221

Dilution: WB=1:500-2000
not yet tested in other applications.
optimal dilutions/concentrations shoμld be determined by the end user.

Purification: affinity purified by Protein A

Specificity: GSTA3 polyclonal Antibody detects endogenous levels of GSTA3 protein.

Molecular Weight: ~25kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: P30115

Product: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Research Use Only