GTPBP5 Polyclonal Antibody
Catalogue Numbers: BS61198-50, BS61198-100
Sizes: 50µl, 100µl
Alternative Name: Mitochondrial ribosome-associated GTPase 2; GTP-binding protein 5; Protein obg homolog 1; ObgH1; MTG2; GTPBP5; OBGH1
Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Swiss-Prot: Q9H4K7
Host: Rabbit
Reactivity: Human, Mouse, Rat
Applications: WB
All Applications: WB: 1:500~1:1000
Background: Small G proteins act as molecular switches for regulation of variety of cellular processes, such as nuclear transport, signal transduction, membrane trafficking and protein synthesis. GTPBP5 (GTP-binding protein 5), also known as OBGH1, is a 406 amino acid small G protein that contains an amino-terminal mitochondria-localization signal. Knockdown of GTPBP5 mRNA results in abnormal nuclear morphologies and elongated mitochondria. In vitro studies demonstrate that GTPBP5 exhibits GTPase activity, cycling between an active GTP-bound state and an inactive GDP-bound state. Activation of GTPases usually results in rearrangements of filamentous actin and the formation of actin stress fibers.
Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: GTPBP5 polyclonal antibody detects endogenous levels of GTPBP5 protein.
Bioworld Molecular Weight: ~ 44 kDa
Note: For research use only, not for use in diagnostic procedure.
Extra Notes: Western blot (WB) analysis of GTPBP5 polyclonal antibody at 1:500 dilution
Line1:A549 whole cell lysate
Line2:Hela whole cell lysate
Line3:PC12 whole cell lysate
Line4:sp20 whole cell lysate
Immunogen: A synthetic peptide corresponding to residues in Human GTPBP5.
Conjugate: Unconjugated
Modification: Unmodified