Product Description

GZMM Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-53442-60, E-AB-53442-120, E-AB-53442-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: GZMM

Target Synonym: GRAM; Granzyme M (lymphocyte met ase 1); Granzyme M; GranzymeM; GZM M; Gzmm; HU Met 1; HU-Met-1; LMET 1; LMET1; Lymphocyte met ase 1; MET 1; Met 1 serine protease; Met ase; Met-1 serine protease; Met-ase; MET1; Met1 serine protease; Natural killer cell granular protease

Research Areas: Cell Biology

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human, Mouse, Rat

Application: WB, IHC, ELISA

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: P51124

Background: GZMM (Granzyme M) is a Protein Coding gene. Diseases associated with GZMM include Adrenal Insufficiency, Congenital, With 46Xy Sex Reversal, Partial Or Complete and Congenital Adrenal Insufficiency. Among its related pathways are Innate Immune System and Granzyme Pathway. GO annotations related to this gene include serine-type endopeptidase activity and endopeptidase activity. An important paralog of this gene is CFD.Human natural killer (NK) cells and activated lymphocytes express and store a distinct subset of neutral serine proteases together with proteoglycans and other immune effector molecules in large cytoplasmic granules. These serine proteases are collectively termed granzymes and include 4 distinct gene products: granzyme A, granzyme B, granzyme H, and the protein encoded by this gene, granzyme M. Two transcript variants encoding different isoforms have been found for this gene.

Concentration: 0.6 mg/mL

Immunogen: Synthetic peptide of human GZMM

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Purification Method: Antigen affinity purification

Dilution: WB 1:500-1:2000, IHC 1:20-1:100, ELISA 1:5000-1:10000

Calculated MW: 28 kDa

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only