HABP2 (50k heavy chain, Cleaved-Arg313) Rabbit Polyclonal Antibody - RA25621

HABP2 (50k heavy chain, Cleaved-Arg313) Rabbit Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA25621-50, RA25621-100

Citations, Manuals and MSDS Available upon request.

Background: hyaluronan binding protein 2 (HABP2) Homo sapiens This gene encodes a member of the peptidase S1 family of serine proteases. The encoded preproprotein is secreted by hepatocytes and proteolytically processed to generate heavy and light chains that form the mature heterodimer. Further autoproteolysis leads to smaller, inactive peptides. This extracellular protease binds hyaluronic acid and may play a role in the coagulation and fibrinolysis systems. Mutations in this gene are associated with nonmedullary thyroid cancer and susceptibility to venous thromboembolism. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed. [provided by RefSeq, Jan 2016],

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage Instructions: -20°C/1 year

Recommended dilutions: WB 1:1000-2000 ELISA 1:5000-20000

Alternative Names: Hyaluronan-binding protein 2 (EC 3.4.21.-;Factor VII-activating protease;Factor seven-activating protease;FSAP;Hepatocyte growth factor activator-like protein;Plasma hyaluronan-binding protein) [Cleaved into: Hyaluronan-binding protein 2 50 kDa heavy chain; Hyaluronan-binding protein 2 50 kDa heavy chain alternate form; Hyaluronan-binding protein 2 27 kDa light chain; Hyaluronan-binding protein 2 27 kDa light chain alternate form]

Applications: WB; ELISA

Species Cross-Reactivity: Human; Mouse; Rat

GeneID (Human): 3026

Protein MW (KDa): 50 77

SWISS: Q14520

Source: Rabbit

Research Use Only