HAND1 Monoclonal Antibody - BT-MCA0661

HAND1 Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA0661-50, BT-MCA0661-100

Citations, Manuals and MSDS Available upon request.

Background: The protein encoded by this gene belongs to the basic helix-loop-helix family of transcription factors. This gene product is one of two closely related family members, the HAND proteins, which are asymmetrically expressed in the developing ventricular chambers and play an essential role in cardiac morphogenesis. Working in a complementary fashion, they function in the formation of the right ventricle and aortic arch arteries, implicating them as mediators of congenital heart disease. In addition, it has been suggested that this transcription factor may be required for early trophoblast differentiation.

Research Areas: Epigenetics and nuclear signaling; Stem cells; Developmental biology; Cardiovascular

Target Protein: HAND1

Applications: WB, ELISA

Reactivity: Human

Clonality: Monoclonal

Host: Mouse

Isotype: IgG

Full Product Name: Heart- and neural crest derivatives-expressed protein 1

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: O96004; Mouse: Q64279

Synonyms: HAND1; BHLHA27; EHAND; Heart- and neural crest derivatives-expressed protein 1; Class A basic helix-loop-helix protein 27; bHLHa27; Extraembryonic tissues; heart; autonomic nervous system and neural crest derivatives-expressed protein 1; eH

GeneID: Human: 9421

Research Use Only