Product Description

HAND1 Polyclonal Antibody

Product: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Catalogue Numbers: BS65120-50, BS65120-100

Sizes: 50µl, 100µl

Swiss-Prot: O96004

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: IHC-p, IF (paraffin section), ELISA

Background: heart and neural crest derivatives expressed 1(HAND1) Homo sapiens The protein encoded by this gene belongs to the basic helix-loop-helix family of transcription factors. This gene product is one of two closely related family members, the HAND proteins, which are asymmetrically expressed in the developing ventricular chambers and play an essential role in cardiac morphogenesis. Working in a complementary fashion, they function in the formation of the right ventricle and aortic arch arteries, implicating them as mediators of congenital heart disease. In addition, it has been suggested that this transcription factor may be required for early trophoblast differentiation. [provided by RefSeq, Jul 2008],

Product: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity: HAND1 Polyclonal Antibody detects endogenous levels of HAND1 protein.

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Immunohistochemical analysis of paraffin-embedded Human brain. Antibody was diluted at 1:100(4° overnight). High-pressure and temperature Tris-EDTA,pH8.0 was used for antigen retrieval. Negetive contrl (right) obtaned from antibody was pre-absorbed by immunogen peptide., Immunohistochemistry analysis of paraffin-embedded human brain tissue, using HAND1 Antibody. The picture on the right is blocked with the synthesized peptide.

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Alternative Name: HAND1; BHLHA27; EHAND; Heart- and neural crest derivatives-expressed protein 1; Class A basic helix-loop-helix protein 27; bHLHa27; Extraembryonic tissues; heart, autonomic nervous system and neural crest derivatives-expressed protein 1; eH

Immunogen: The antiserum was produced against synthesized peptide derived from human HAND1. AA range:71-120

Conjugate: Unconjugated

Modification: Unmodified