HAND2 Polyclonal Antibody - E-AB-61488

HAND2 Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-61488-60, E-AB-61488-120, E-AB-61488-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: HAND2

Target Synonym: HAND2; DHAND2; Hed; Thing2; bHLHa26; dHand

Research Areas: Cardiovascular, Epigenetics and Nuclear Signaling, Neuroscience

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human, Mouse, Rat

Application: WB, IF

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: P61296

Background: The protein encoded by this gene belongs to the basic helix-loop-helix family of transcription factors. This gene product is one of two closely related family members, the HAND proteins, which are asymmetrically expressed in the developing ventricular chambers and play an essential role in cardiac morphogenesis. Working in a complementary fashion, they function in the formation of the right ventricle and aortic arch arteries, implicating them as mediators of congenital heart disease. In addition, this transcription factor plays an important role in limb and branchial arch development.

Concentration: 1mg/mL

Immunogen: Recombinant fusion protein of human HAND2 (NP_068808.1).

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification Method: Affinity purification

Dilution: WB 1:500-1:2000 IF 1:50-1:100

Calculated MW: 20kDa/23kDa

Observed MW: 26kDa

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only