Product Description

HAO1 Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS67321-50, BS67321-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Broad substrate specificity (S)-2-hydroxy-acid oxidase that preferentially oxidizes glycolate.The glyoxylate produced by the oxidation of glycolate can then be utilized by alanine-glyoxylate aminotransferase for the peroxisomal synthesis of glycine, this pathway appears to be an important step for the detoxification of glyoxylate which, if allowed to accumμlate, may be metabolized to oxalate with formation of kidney stones.Can also catalyze the oxidation of glyoxylate, and long chain hydroxyacids such as 2-hydroxyhexadecanoate and 2-hydroxyoctanoate, albeit with much lower catalytic efficiency.Active in vitro with the artificial electron acceptor 2, 6-dichlorophenolindophenol (DCIP), but O2 is believed to be the physiological electron acceptor, leading to the production of H2O2.Is not active on L-lactate and 2-hydroxybutanoate.

Category: Primary Antibody

Reactivity: Human, Mouse

Host: Rabbit

Applications: WB, IHC

Alternate Names: GOX1, HAOX1, Hydroxyacid oxidase 1, HAOX1, Glycolate oxidase, GOX

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: Recombinant fμll length protein of human HAO1

Dilution: WB (1/500 - 1/2000), IHC (1/50 - 1/200)

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: Recognizes endogenous levels of HAO1 protein.

Molecular Weight: ~40 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: Q9UJM8

Product: Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Research Use Only