HAP1 Polyclonal Antibody - RA32593

HAP1 Polyclonal Antibody Sizes: 50μL, 100μL Catalogue Numbers: RA32593-50, RA32593-100 Citations, Manuals and MSDS Available upon request. Background: huntingtin associated protein 1 (HAP1) Homo sapiens Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein that interacts with huntingtin, with two cytoskeletal proteins (dynactin and pericentriolar autoantigen protein 1), and with a hepatocyte growth factor-regulated tyrosine kinase substrate. The interactions with cytoskeletal proteins and a kinase substrate suggest a role for this protein in vesicular trafficking or organelle transport. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008], Condition: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. Storage Instructions: -20°C/1 year Recommended dilutions: WB 1:500-2000 ELISA 1:5000-20000 Applications: WB; ELISA Species Cross-Reactivity: Human; Rat; Mouse GeneID (Human): 9001 Protein MW (KDa): 73 SWISS: P54257 Source: Rabbit Research Use Only