HAP1 Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A16333-20, A16333-100
Citations, Manuals and MSDS Available upon request.
Background: Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein that interacts with huntingtin, with two cytoskeletal proteins (dynactin and pericentriolar autoantigen protein 1), and with a hepatocyte growth factor-regulated tyrosine kinase substrate. The interactions with cytoskeletal proteins and a kinase substrate suggest a role for this protein in vesicular trafficking or organelle transport. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Category: Polyclonal Antibodies
Applications: WB, ELISA
Cross-reactivity: Mouse, Rat
Protein Weight: 76kDa
Observed Molecular Weight: 76kDa
Immunogen: Recombinant protein (or fragment)
Species: Human
GeneID: 9001
SWISS: P54257
Alternate Names: HLP; HAP2; HIP5; hHLP1; HAP1
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal, 50% glycerol, pH 7.3.
Recommended Dilutions: WB, 1:500 - 1:2000 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Signal Transduction, Neuroscience, Neurodegenerative Diseases.
NCBI Alias: HAP1
Research Use Only